chemical constituents and antibacterial activity of essential oil of peucedanum ruthenicum m. bieb. fruits
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abstract
the essential oil of peucedanum ru t h e n i c u m fruits, obtained by hydrodistillation, was analyzed by gas chromatography and gas chromatography mass spectrometry. among the 31 identified constituents accounting for 83.9% of the total oil, the major components were 1,8-cineole (11.15%), camphor (5.86%), z-carveol (6.88%), l-carvone (5.61%), 8,9-dehydroisolongifolene (11.35%), caryophyllene oxide (13.65%), and caryophylla-4(12),8(13)-dien-5-β-ol (5.19%). antimicrobial activity of the essential oil was investigated against various gram-positive and gram-negative bacteria. the essential oil of p. ruthenicum showed activity against gram-positive bacteria but had no effect on the tested gram negative bacteria.
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Journal title:
iranian journal of pharmaceutical sciencesجلد ۱، شماره ۴، صفحات ۲۱۷-۲۲۲
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